Analysis of an intronic promoter within Synj2.
Biochem. Biophys. Res. Commun.2013 Nov 1;440(4):640-5. Epub 2013 Oct 05
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摘要
Synj2 (synaptojanin 2) encodes an inositol polyphosphate phosphatase that functions in recycling neurotransmitter vesicles and is implicated in spermatogenesis. Transcription of Synj2 is thought to occur from one of two promoters based on analysis of a variable 5' untranslated region. Clustering all known mouse Synj2 transcripts led us to uncover a novel subset of transcripts that appears to derive from a region located within intron 7. We identified two alternate splice variants emanating from use of this promoter. These alternate splice variants manifest developmental stage specificity and somatic versus gametic differences in expression.
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基因功能
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原始数据
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文献解读
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