Genomic analysis of a novel spontaneous albino C57BL/6N mouse strain.
Genesis. 2013 Jul;51(7):523-8. doi:10.1002/dvg.22398. Epub 2013 May 25
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摘要
We report an albino C57BL/6N mouse strain carrying a spontaneous mutation in the tyrosinase gene (C57BL/6N-Tyr(cWTSI)). Deep whole genome sequencing of founder mice revealed very little divergence from C57BL/6NJ and C57BL/6N (Taconic). This coisogenic strain will be of great utility for the International Mouse Phenotyping Consortium (IMPC), which uses the EUCOMM/KOMP targeted C57BL/6N ES cell resource, and other investigators wishing to work on a defined C57BL/6N background.
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基因功能
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原始数据
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文献解读
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