The role of inflammatory chemokines in lymphoid neoorganogenesis in breast cancer.
Biomed. Pharmacother.2013 Jun;67(5):363-6. Epub 2013 Apr 03
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摘要
The expression profiling analysis of inflammatory chemokines and their receptors in newly formed lymph nodes in breast cancer was carried out. The analysis revealed the increase in expression of the genes CCL16, XCR1, CYFIP2, TNFSF14 and the reduction in expression of chemokine ligands CXCL5 and CXCL12 in tertiary lymphoid organs. The obtained results allow us to suggest that the process of induction of lymph nodes neogenesis is identical (in its key mechanisms) to the process of lymphoid tissue neogenesis in autoimmune diseases and in some infections, but may have different triggers.
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基因功能
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原始数据
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文献解读
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