Exonic resequencing of the DLGAP3 gene as a candidate gene for schizophrenia.

Psychiatry Res. 2013 Jun 30;208(1):84-7. Epub 2013 Feb 13

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摘要

We resequenced the exonic regions of the DLGAP3 gene, which encodes SAP90/PSD95-associated protein 3, in 215 schizophrenic patients and 215 non-psychotic controls. Seven known single-nucleotide polymorphisms (SNPs) were identified, but not associated with schizophrenia. Nevertheless, we identified several rare missense mutations and some of them might be associated with the pathogenesis of schizophrenia.

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Exonic resequencing of the DLGAP3 gene as a candidate gene for schizophrenia.

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