Palmitoylation and the trafficking of peripheral membrane proteins.

Biochem. Soc. Trans.2013 Feb 01;41(1):62-6

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Palmitoylation, the attachment of palmitate and other fatty acids on to cysteine residues, is a common post-translational modification of both integral and peripheral membrane proteins. Dynamic palmitoylation controls the intracellular distribution of peripheral membrane proteins by regulating membrane-cytosol exchange and/or by modifying the flux of the proteins through vesicular transport systems.

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Palmitoylation and the trafficking of peripheral membrane proteins.

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