Characterization of an acid-inducible sulfatase in Salmonella enterica serovar typhimurium.
Appl. Environ. Microbiol.2013 Mar;79(6):2092-5. Epub 2013 Jan 11
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摘要
Sulfatases of enteric bacteria can provide access to heavily sulfated mucosal glycans. In this study, we show that aslA (STM0084) of Salmonella enterica serovar Typhimurium LT2 encodes a sulfatase that requires mildly acidic pH for its expression and activity. AslA is not regulated by sulfur compounds or tyramine but requires the EnvZ-OmpR and PhoPQ regulatory systems, which play an important role in pathogenesis.
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基因功能
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原始数据
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文献解读
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