A beginner's guide to eukaryotic genome annotation.

Nat. Rev. Genet.2012 Apr 18;13(5):329-42

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摘要

The falling cost of genome sequencing is having a marked impact on the research community with respect to which genomes are sequenced and how and where they are annotated. Genome annotation projects have generally become small-scale affairs that are often carried out by an individual laboratory. Although annotating a eukaryotic genome assembly is now within the reach of non-experts, it remains a challenging task. Here we provide an overview of the genome annotation process and the available tools and describe some best-practice approaches.

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A beginner's guide to eukaryotic genome annotation.

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