Structures of the rat complement regulator CrrY.
Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun.2011 Jul 01;67(Pt 7):739-43. Epub 2011 Jun 23
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摘要
Complement receptor 1-related protein Y (CrrY) is an important cell-surface regulator of complement that is unique to rodent species. The structure of rat CrrY domains 1-4 has been determined in two distinct crystal forms and reveals a 70° bend between domains 3 and 4. Comparisons of this structure with those of other complement regulators suggests that rearrangement of this interface may occur on forming the regulatory complex with C3b.
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文献解读
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