Human bitter taste receptors hTAS2R8 and hTAS2R39 with differential functions to recognize bitter peptides.

Biosci. Biotechnol. Biochem.2011;75(6):1188-90. Epub 2011 Jun 13

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摘要

The strong bitter peptide, Phe-Phe-Pro-Arg, activated cultured cells expressing either of the known human bitter taste receptors, hTAS2R8 and hTAS2R39. The partial structure of Pro-Arg activated hTAS2R39, but did not activate hTAS2R8. These receptors may not indiscriminately recognize bitter peptides, but have a differential function in their recognition.

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Human bitter taste receptors hTAS2R8 and hTAS2R39 with differential functions to recognize bitter peptides.

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