The role of memory-related gene polymorphisms, KIBRA and CLSTN2, on replicate memory assessment in the elderly.
J Neural Transm (Vienna). 2012 Jan;119(1):77-80. doi:10.1007/s00702-011-0667-9. Epub 2011 Jun 04
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摘要
The role of the CLSTN2 (rs6439886) and KIBRA (rs17070145) SNPs in cognitive impairment was analysed in a 75-76Â years old group. Various memory assessment tests were carried out on individuals at baseline and during follow-up investigations, and biallelic genotyping was performed. No influence of the allele status of either SNPs was observed on any memory test. No increased risk of any type of late development, and cognitive impairment was associated with rs6439886 or rs17070145.
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基因功能
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原始数据
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文献解读
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