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Arabidopsis cryptochrome 1 interacts with SPA1 to suppress COP1 activity in response to blue light.

Genes Dev. 2011 May 15;25(10):1029-34. Epub 2011 Apr 21
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摘要


Plant photoreceptors mediate light suppression of the E3 ubiquitin ligase COP1 (CONSTITUTIVE PHOTOMORPHOGENIC 1) to affect gene expression and photomorphogenesis. However, how photoreceptors mediate light regulation of COP1 activity remains unknown. We report here that Arabidopsis blue-light receptor cryptochrome 1 (CRY1) undergoes blue-light-dependent interaction with the COP1-interacting protein (SUPPRESSOR OF PHYTOCHROME A). We further show that the interaction suppresses the interaction and COP1-dependent degradation of the transcription factor HY5. These results are consistent with a hypothesis that photoexcited CRY1 interacts with duanyu18421 to modulate COP1 activity and plant development.

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基因功能


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