Identification of novel nuclear protein interactions with the N-terminal part of filamin A.

Biosci. Biotechnol. Biochem.2011;75(1):145-7. Epub 2011 Jan 07

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Since certain missense mutations in the N-terminal part of filamin A (FLNA) cause inherited skeletal malformation, we screened for proteins that bind to this part of FLNA. We identified two nuclear proteins that are specifically associated with the N-terminal region of FLNA. This suggests more extensive nuclear function of filamin than expected.

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Identification of novel nuclear protein interactions with the N-terminal part of filamin A.

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