Novel single nucleotide polymorphism identification in interleukin-6 gene of Pakistani sheep.
Mol Biol Rep. 2011 Mar;38(3):2151-4. doi:10.1007/s11033-010-0342-5. Epub 2010 Sep 29
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摘要
The present study aimed to identify single-nucleotide polymorphism (SNP) in coding and non-coding regions of interleukin-6 (IL-6) gene of Pakistani sheep. The IL-6 gene of 205 animals from nine sheep breeds were sequenced for screening of SNP. Characterizing the IL-6 gene revealed thirteen SNP sites within the intronic region of IL-6 gene. The novel SNPs found in the present study can serve as genetic marker for association studies with susceptibility/resistance to parasite infection in sheep. This is first report of SNP polymorphism of IL-6 gene of Pakistani sheep.
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基因功能
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原始数据
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文献解读
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