SprB is the molecular link between Salmonella pathogenicity island 1 (SPI1) and SPI4.

J Bacteriol. 2010 May;192(9):2459-62. Epub 2010 Feb 26

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摘要

Salmonella pathogenicity island 1 (SPI1) and SPI4 have previously been shown to be jointly regulated. We report that SPI1 and SPI4 gene expression is linked through a transcriptional activator, SprB, encoded within SPI1 and regulated by HilA. SprB directly activates SPI4 gene expression and weakly represses SPI1 gene expression through HilD.

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SprB is the molecular link between Salmonella pathogenicity island 1 (SPI1) and SPI4.

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