Expression of Epiplakin1 in the developing and adult mouse retina.
[No authors listed]
摘要
PURPOSE:To assess the expression of Epiplakin1 (Eppk1) in the developing and adult mouse retina. METHODS:Eppk1 expression was examined using reverse transcription-polymerase chain reaction (RTPCR) analysis and immunoblot analysis. The Eppk1 expression pattern was examined by immunohistochemical analysis in embryonic and adult C57BL/6J mice. RESULTS:Both Eppk1 mRNA and protein were detected in adult mouse retina. Eppk1 was expressed in nestin-positive neural progenitor cells in the embryonic retina. In adults, Eppk1 was expressed in retinal ganglion cells, bipolar cells, and Müller glial cells. CONCLUSIONS:These results suggest that Eppk1 is expressed both in embryonic and adult retina and may be involved in retinal development.
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基因功能
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原始数据
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文献解读
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