The role of mucin-type O-glycans in eukaryotic development.
Semin Cell Dev Biol. 2010 Aug;21(6):616-21. Epub 2010 Feb 06
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摘要
Newly emerging genetic studies have revealed that a subset of the family of glycosyltransferases responsible for the formation of mucin-type O glycans is essential for normal development. As additional genetic, biochemical and physical tools are developed to interrogate the complex structure and surface location of this under-studied class of carbohydrate, no doubt additional roles will be elucidated.
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文献解读
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