The physiological stimulus for the BarA sensor kinase.
J. Bacteriol.2010 Apr;192(7):2009-12. Epub 2010 Jan 29
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摘要
The two-component signal transduction system (TCS) BarA/UvrY activates transcription of CsrB and CsrC noncoding RNAs, which act by sequestering the RNA-binding global regulatory protein CsrA. Here, we show that the metabolic end products formate and acetate provide a physiological stimulus for this TCS and thus link posttranscriptional regulation by the Csr system to the metabolic state of the cell.
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基因功能
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原始数据
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文献解读
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