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The CheZ binding interface of CheAS is located in alpha-helix E.

J Bacteriol. 2009 Sep;191(18):5845-8. Epub 2009 Jul 06
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摘要


Specific CheA-short (CheA(S)) residues, L123 and L126, were identified as critical for CheZ binding. In the CheA(S) 'P1-CheZ nuclear magnetic resonance structure, these residues form an interaction surface on alpha-helix E in the 'P1 domain. Both L123 and L126 are buried in CheA-long (CheA(L)), providing an explanation for why CheA(L) fails to bind CheZ.

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