The Rcs two-component system regulates expression of lysozyme inhibitors and is induced by exposure to lysozyme.
J. Bacteriol.2009 Mar;191(6):1979-81. Epub 2009 Jan 09
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摘要
The Escherichia coli Rcs regulon is triggered by antibiotic-mediated peptidoglycan stress and encodes two lysozyme inhibitors, Ivy and MliC. We report activation of this pathway by lysozyme and increased lysozyme sensitivity when Rcs induction is genetically blocked. This lysozyme sensitivity could be alleviated by complementation with Ivy and MliC.
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基因功能
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原始数据
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文献解读
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