Cytoskeletal regulation: coordinating actin and microtubule dynamics in membrane trafficking.
Curr. Biol.2008 Sep 23;18(18):R873-5
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摘要
The Arp2/3 complex is essential for actin nucleation and filament elongation in a variety of intracellular processes. This functional versatility is exerted through the regulation of its activity by nucleation-promoting factors (NPFs). The discovery of a new NPF, WHAMM, reveals unexpected connections between the actin and microtubule cytoskeletons and membrane dynamics during ER-to-Golgi transport.
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基因功能
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原始数据
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文献解读
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