Introduction to bacterial signal transduction networks.
Adv. Exp. Med. Biol.2008;631:1-6. doi:10.1007/978-0-387-78885-2_1
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摘要
Transcriptional analysis using a DNA microarray is an extremely efficient method for analyzing two-component signal transduction networks. Here we introduce three such networks in Escherichia coli that were clarified using a DNA microarray: a PhoQ/PhoP system that senses extracellular Mg2+ and controls the gene expression for adaptation to environmental Mg2+ deprivation (Mg2+ stimulon); an EvgS/EvgA signal transduction system that activates expression of multiple drug efflux pumps and acid resistance genes; and a signal transduction cascade between EvgS/EvgA and PhoQ/PhoP.
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基因功能
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原始数据
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文献解读
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