The CorA Mg2+ channel is required for the virulence of Salmonella enterica serovar typhimurium.
J Bacteriol. 2008 Oct;190(19):6517-23. Epub 2008 Aug 01
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摘要
CorA is the primary Mg(2+) channel in Salmonella enterica serovar Typhimurium. A corA mutant is attenuated in mice and defective for invasion of and replication within epithelial cells. Microarray studies show that several virulence effectors are repressed in a corA mutant strain, which ultimately manifests itself as a decrease in virulence.
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