The concept of translocational regulation.
J Cell Biol. 2008 Jul 28;182(2):225-32. Epub 2008 Jul 21
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摘要
Biological processes are regulated to provide cells with exquisite adaptability to changing environmental conditions and cellular demands. The mechanisms regulating secretory and membrane protein translocation into the endoplasmic reticulum (ER) are unknown. A conceptual framework for translocational regulation is proposed based on our current mechanistic understanding of ER protein translocation and general principles of regulatory control.
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文献解读
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