The effect of MinC on FtsZ polymerization is pH dependent and can be counteracted by ZapA.
FEBS Lett.2008 Jul 23;582(17):2601-8. Epub 2008 Jun 25
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摘要
The min system prevents polar cell division in bacteria. Here, the biochemical characterization of the interaction of MinC and FtsZ from a Gram-positive bacterium, Bacillus subtilis, is reported. B. subtilis MinC inhibits FtsZ polymerization in a pH-dependent manner by preventing the formation of lateral associations between filaments. The inhibitory effect of MinC on FtsZ polymerization is counteracted by the presence of ZapA, a protein that promotes FtsZ filament bundling.
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基因功能
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原始数据
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文献解读
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