siRNA-mediated inhibition of phosphatidylinositol glycan Class B (PIGB) confers resistance to methylmercury in HEK293 cells.
J Toxicol Sci. 2007 Dec;32(5):581-3
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摘要
We performed functional gene screening, using a siRNA library targeting 8,500 human genes, to identify proteins that are involved in the susceptibility of cells to methylmercury. Screening revealed that downregulation of the gene for phosphatidylinositol glycan class B (PIGB) by siRNA confers resistance to methylmercury in HEK293 cells.
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基因功能
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原始数据
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文献解读
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