Critical role of a single position in the -35 element for promoter recognition by Mycobacterium tuberculosis SigE and SigH.

J. Bacteriol.2008 Mar;190(6):2227-30. Epub 2008 Jan 11

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摘要

Mycobacterial SigE and SigH both initiate transcription from the sigB promoter, suggesting that they recognize similar sequences. Through mutational and primer extension analyses, we determined that SigE and SigH recognize nearly identical promoters, with differences at the 3' end of the -35 element distinguishing between SigE- and SigH-dependent promoters.

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Critical role of a single position in the -35 element for promoter recognition by Mycobacterium tuberculosis SigE and SigH.

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