The deoxycytidine pathway for thymidylate synthesis in Escherichia coli.

J. Bacteriol.2007 Nov;189(21):7922-6. Epub 2007 Sep 07

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摘要

When thymidylate production is diminished by a mutation affecting dCTP deaminase, Escherichia coli is known to use an alternate pathway involving deoxycytidine as an intermediate. The pathway requires the gene for any of three nucleoside diphosphate kinases (ndk, pykA, or pykF) and the gene for a 5'-nucleotidase (yfbR).

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The deoxycytidine pathway for thymidylate synthesis in Escherichia coli.

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