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Mitotic motors: kinesin-5 takes a brake.

Curr. Biol.2007 Jul 17;17(14):R544-7
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摘要


A kinesin-5-dependent 'sliding filament' mechanism is commonly used to actively push apart the poles during mitotic spindle assembly and elongation, but a recent study now shows that, in C. elegans, kinesin-5 is deployed as a brake to slow down spindle-pole separation.

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