Rate of evolution in brain-expressed genes in humans and other primates.
[No authors listed]
摘要
Brain-expressed genes are known to evolve slowly in mammals. Nevertheless, since brains of higher primates have evolved rapidly, one might expect acceleration in DNA sequence evolution in their brain-expressed genes. In this study, we carried out full-length cDNA sequencing on the brain transcriptome of an Old World monkey (OWM) and then conducted three-way comparisons among (i) mouse, OWM, and human, and (ii) OWM, chimpanzee, and human. Although brain-expressed genes indeed appear to evolve more rapidly in species with more advanced brains (apes > OWM > mouse), a similar lineage effect is observable for most other genes. The broad inclusion of genes in the reference set to represent the genomic average is therefore critical to this type of analysis. Calibrated against the genomic average, the rate of evolution among brain-expressed genes is probably lower (or at most equal) in humans than in chimpanzee and OWM. Interestingly, the trend of slow evolution in coding sequence is no less pronounced among brain-specific genes, vis-Ã -vis brain-expressed genes in general. The human brain may thus differ from those of our close relatives in two opposite directions: (i) faster evolution in gene expression, and (ii) a likely slowdown in the evolution of protein sequences. Possible explanations and hypotheses are discussed.
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基因功能
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基因
LOC101864760, LOC101864762, LOC101864764, LOC101864765, LOC101864768, LOC101864772, LOC101864773, LOC101864776, PYCR2, FADS1, LOC101864780, LOC101864782, NAA15, CKMT1A, ZC3H12B, LOC101864787, SMUG1, LOC101864792, SNW1, LETMD1, PID1, LOC101864798, LOC101864799, NREP, KDM3A, LOC101864802, SLC44A3, METTL2A, PPP1R12A, FAM136A, LOC101864808, DHX15, RXRG, KPNA2, C3H7orf43, HP1BP3, THOC1, LOC101864820, RBM25, PPP4R3A, TMEM87A, ZNF24, DNAJA2, LOC101864827, LOC101864828, ACP2, LOC101864830, LOC101864831, EDEM2, LOC101864834, RPSA, LOC101864838, LOC101864840, TMEM199, PSTK, NUDT9, TMEM143, LOC101864848, AP3M1, C15H9orf3, LOC101864851, COG2, SLC33A1, PAICS, EEF1A2, PNISR, ITSN2, LIG1, LOC101864860, TNPO1, LOC101864862, SEC14L2, MRPS11, LOC101864866, LOC101864867, USP30, SPTLC1, VIM, VCP, SNX32, SNRPA, ERP44, RFTN2, KIAA0196, DNAJB14, TPM1, ZZEF1, LOC101864885, UBE2E3, FSHB, KIAA1109, PDP1, LOC101864891, LOC101864893, LPAR1, LOC101864895, SAP18, LOC101864897, PRDX3, LPAR4, TCP11L1, CAMK4, LOC101864902, STT3B, CECR5, TMEM263, TRA2B, KALRN, LOC101864911, BBOX1, SAMM50, LOC101864917, TNFSF10, GSN, RPS25, TMEM41B, PIM2, LOC101864927, TRAP1, FBXO36, DGKI, LOC101864934, VAMP2, FKBPL, EVI2B, TMA16, PHACTR2, LOC101864942, IDI1, GTF2F2, LOC101864946, RHOBTB3, LOC101864951, LOC101864952, EIF3G, AZIN1, LOC101864956, LOC101864957, NEK3, SNAP23, FAM13B, BCLAF1, HEATR6, SAAL1, LOC101864970, GABARAPL1, LOC101864972, MAP7D3, LOC101864974, LOC101864976, MPL, LOC101864980, NSFL1C, VDAC1, ACSBG1, LOC101864985, ITM2C, LOC101864988, NOTCH2, LOC101864990, SYNDIG1, EIF4H, STMN2, LOC101864997, LOC101864999, HMGB1, MRPS15, PRPF19, RTN4, LOC101865008, RPL22, CD2BP2, LOC101865011, VCPKMT, AMFR, CTSB, LOC101865018, LOC101865019, LOC101865020, PER1, LOC101865022, LOC101865023, SNX4, LOC101865028, MPC1, EMC1, LOC101865032, GABRA4, LYPD1, NPHP4, LOC101865039, LOC101865040, APH1A, LOC101865044, LOC101865046, LOC101865047, LOC101865048, LOC101865049, IDH3A, PSMC5, PRRC2B, PHYHIP, BMI1, HAPLN2, FDPS, LOC101865060, MED13L, PLEKHB2, COLGALT2, TCEAL1, CRK, LOC101865066, LOC101865067, ATPAF2, LOC101865071, ARF5, LOC101865073, RPS6KA4, ENO1, OGFOD1, LOC101865080, LOC101865082, RHEBL1, LOC101865084, LOC101865085, LOC101865086, LINGO2, PROS1, LOC101865089, MYO1B, LOC101865092, C1H1orf56, DUSP14, LOC101865097, LOC101865098, LOC101865101, LOC101865102, GPI, SPRED2, ZMYM3, LOC101865110, SLC13A3, LOC101865114, RRP15, HACD3, LOC101865118, SDHB, LOC101865121, LOC101865122, PPME1, LOC101865128, LOC101865130, MED4, CSTF1, RITA1, LOC101865136, EPS15, TM7SF2, FSD1, SLC25A36, LOC101865141, ZC3H8, LOC101865144, LOC101865145, LOC101865146, LOC101865147, NXN, NUCKS1, LOC101865152, LOC101865153, LOC101865154, GPSM2, LOC101865156, SMARCA4, LOC101865158, SPTBN1, LOC101865161, CHID1, FBL, RAPGEF4, LOC101865167, CALM2, ARID5B, RNPC3, DYNC1I2, CNDP2, FAM83D, LOC101865180, FBXO11, LONRF1, EXOC7, RRAGA, KCNJ1, SRR, ABHD6, SRSF1, ZCCHC12, NUP205, PTCHD1, PPP2R4, LOC101865204, CHTOP, LRRC61, TRIM2, GMPPA, DNAJC24, RPS7, ZBTB8OS, LOC101865215, PTPN1, RMDN3, GBF1, LOC101865221, LOC101865222, PIK3C2A, ZNF574, LOC101865227, SRPRB, LOC101865229, LOC101865231, C1QTNF3, MBTPS1, ANO3, TBRG1, NDUFS1, NDUFB2, LOC101865241, CHD3, STX12, ACAD9, CAMK1G, AHCY, KIAA1210, LOC101865251, CLASP2, WDR77, LOC101865254, TMEM131, LTBP4, LOC101865263, UGP2, LSM8, LOC101865273, ZNF84, LOC101865275, MAP3K4, PRKAG1, LOC101865280, KIF1B, LOC101865284, LOC101865285, LOC101865287, CSRP1, RPL13A, LOC101865292, EIF4E3, LOC101865295, ATP1B3, MRAS, LOC101865298, LOC101865299, LOC101865300, EIF3I, LOC101865302, LOC101865303, TMEM237, LOC101865307, LOC101865308, NDN, ANK2, MICU2, LOC101865314, ASL, STAU1, LOC101865317, LOC101865318, RNF19A, HSPB1, LOC101865325, SGCE, TMEM97, TP53RK, LOC101865331, DDX39B, OXT, LOC101865334, LOC101865335, NEK2, PARVB, LOC101865343, LOC101865344, KCTD15, SERINC3, SRSF7, MAPRE1, LOC101865349, RDX, CASP8, YY1AP1, TRAPPC10, RSL24D1, PDXP, IP6K1, NLK, BCAS2, C8H8orf46, PHF11, NCALD, CCNH, LOC101865369, LOC101865370, GPR34, P2RX7, LOC101865375, LOC101865376, LOC101865378, LOC101865379, GSTA4, POLR2C, NDRG4, UBXN6, ABCD3, ITPR1, LOC101865390, SUMO3, ESD, LOC101865395, KLF9, ELMO2, LOC101865401, PCP4L1, N4BP2L1, ASNS, LOC101865410, LOC101865412, FAM73B, LOC101865414, RPL14, KPNB1, LOC101865418, PERP, ECI2, MSMO1, SYT1, MAG, CCDC80, LOC101865427, GANAB, PET100, LOC101865430, LOC101865431, LOC101865432, EXTL3, PDIA6, LOC101865435, LOC101865436, LOC101865437, LOC101865442, PLOD1, CCDC136, SNAI2, LOC101865452, KIF5A, DPCD, MED17, LOC101865457, LOC101865460, CAPN7, LOC101865463, AFTPH, HIBCH, LOC101865467, FBXO33, DHX36, LOC101865471, ASS1, LOC101865474, ZNF711, ZDHHC17, PPP2R1B, PSMA3, MIS12, UBTF, LOC101865481, HADH, LACTB2, FUT8, LOC101865485, LOC101865487, CEP120, LOC101865489, TRAPPC9, LOC101865492, LOC101865494, FAM134B, KLC1, TMEM59, GPD1, LOC101865503, UCK1, LOC101865507, CEP162, C6H5orf15, LOC101865512, LOC101865517, NEGR1, ME3, MAN2B2, MVP, EIF1AX, DAZAP1, TECPR2, KCND2, SPTAN1, TIAM1, LOC101865531, CORO7, PRDX5, PPFIA4, LOC101865535, AKR1C1, LOC101865537, LOC101865538, LOC101865540, MMP2, LOC101865545, LOC101865546, LOC101865549, LOC101865550, SLC41A3, CDK18, DNAJC7, NEFL, DAP, TRIM36, LOC101865567, LOC101865568, LOC101865569, LOC101865572, LOC101865573, PCF11, NECAB1, ADGRL4, LOC101865578, SNRNP40, WDR46, POLR2E, LOC101865585, LOC101865586, MFAP1, LOC101865590, BUB3, UEVLD, TAOK3, PSPC1, FBXO27, RDH12, LOC101865598, ANXA6, MRS2, MAP2, GPBP1L1, LOC101865603, CRYZ, MYO6, LOC101865608, LOC101865609, LOC101865610, LOC101865611, IFFO1, PTBP2, TMEM126B, QARS, LOC101865618, LOC101865619, LOC101865620, RNASET2, LOC101865622, VDAC2, RHOA, LOC101865631, LOC101865633, LOC101865634, LOC101865636, CAMK2G, RUBCN, PLXNA2, NUTF2, LOC101865642, COPS8, LOC101865644, RGS3, CAV1, SCARB2, EVI2A, LOC101865650, DCLK1, NUDT16, AIMP1, C3H7orf50, LOC101865658, ACAT2, PROM1, HMGB2, GOT1, LOC101865669, ACAA2, LSG1, OAZ2, PAAF1, NCOA4, LOC101865676, PKM, ZNF35, LOC101865681, RCAN2, CCDC126, LOC101865684, LOC101865688, ZNF385A, SIRT2, LOC101865692, LOC101865694, CPLX2, LOC101865697, SRP72, RBM3, ACVR1B, AGPAT5, LOC101865705, RAPGEF3, LOC101865710, ZNF544, GALNT11, LOC101865713, LOC101865714, LOC101865717, DEDD2, ZCCHC9, LOC101865722, LOC101865723, CALCOCO2, PANX2, LOC101865729, NONO, LOC101865733, PPFIA1, LOC101865735, MDH1, LOC101865738, LOC101865741, ZNF394, GAB1, PNMAL1, PPP2R5D, LOC101865750, KIAA1324L, LOC101865753, HOPX, RTFDC1, LOC101865758, LOC101865759, LOC101865760, ALDH1A1, LOC101865766, LOC101865767, PAFAH1B2, DLG4, CBLN2, TUBA1A, LOC101865774, TCTN1, FAM178B, C4H6orf89, XPO7, WDR91, PLEKHG5, REEP5, CHD6, SERPINB1, VLDLR, DNAJC11, LOC101865791, NXF1, EEF1G, LOC101865799, LOC101865800, LOC101865802, MROH8, RPF1, FABP7, PSMB5, THRA, ARL6, TMBIM6, SF3A3, LOC101865813, NUP85, SPAG7, DTNA, LOC101865820, TMEM130, LOC101865822, EIF2AK1, LOC101865824, NOA1, UBE2K, NFYC, ST6GALNAC6, MAN2A1, LOC101865833, SIDT2, LOC101865837, LOC101865838, LOC101865839, SH3GL3, CDC23, MRPL27, PEX3, MMADHC, HSF4, TMEM161B, THADA, RPH3A, RPS16, PRPF4B, CLIC4, LOC101865860, CARS2, LOC101865863, LOC101865865, LOC101865867, SMARCA1, LOC101865870, LOC101865871, CDK5, MAT2A, TBC1D15, LOC101865878, FDCSP, PALMD, RHNO1, LOC101865885, NRSN1, LOC101865890, NOP2, PARK7, TARS2, WIPI2, LOC101865896, FOCAD, SPATA6L, LOC101865900, MEIS2, LOC101865902, SHMT2, C14H11orf49, GBE1, LOC101865908, DNAJC6, BRMS1, LOC101865913, NEMF, LOC101865917, TALDO1, LOC101865919, LOC101865920, YAF2, LOC101865922, AP1G1, DDX41, EGLN3, SNRPB2, ALG1, LOC101865929, LOC101865930, PEX14, SAE1, LOC101865933, LOC101865934, LOC101865935, SMPD4, GPR146, TMED10, LOC101865941, LOC101865942, RAB34, LOC101865944, LOC101865945, DNMBP, LOC101865947, COLEC11, LOC101865949, LOC101865952, LOC101865954, VMO1, LOC101865957, EMC4, IST1, LOC101865960, RAB5B, MKRN2, LOC101865963, PSMC3, FNTB, ATG13, TOB2, LOC101865974, TAB2, LOC101865976, LOC101865978, MRPS18B, YME1L1, NEFM, DTX4, HS3ST1, DEF8, LOC101865988, PGRMC2, B3GALT2, FRY, ZNF577, GRIA3, LOC101865996, SEZ6, CCND3, LOC101866001, LOC101866003, GLT8D1, ALG6, GNA14, LOC101866011, FBXO9, FAM175B, SAFB, DARS, LOC101866021, LOC101866024, RFC1, LOC101866028, ADIPOR1, LOC101866031, KLHL1, SARNP, ITGAM, LOC101866038, HTATSF1, HINFP, RNASEK, MGST2, LOC101866046, LOC101866048, OXCT1, LOC101866053, SLC29A1, LOC101866057, FBXO7, SHISA5, LOC101866061, MLF2, LOC101866064, LOC101866065, DCAF8, CA2, CALD1, PPP3CB, LOC101866071, HERPUD2, LOC101866074, VAMP7, LOC101866076, GPM6B, NIP7, CFAP36, LOC101866085, LOC101866087, RDH11, LOC101866089, NUP58, HIF1A, LOC101866094, LOC101866095, LOC101866096, RPL5, VPS8, LOC101866100, LOC101866101, LOC101866102, LOC101866103, LOC101866104, OSER1, RPL24, N4BP2L2, TTYH1, AKAP6, LOC101866117, RUNDC3A, C1QTNF1, TSPAN5, HSPB6, ST6GALNAC5, LOC101866128, LOC101866130, LOC101866131, PAK1, LOC101866134, CCDC90B, LOC101866137, SLIT2, SCG2, FOLH1B, LOC101866141, DCN, LOC101866145, LOC101866147, RBFOX1, ARF4, LOC101866151, BORCS5, MPHOSPH10, LOC101866155, FEZ1, MRPL55, CFAP43, LOC101866159, LOC101866160, CMPK2, PI4KB, CCPG1, RPL9, UNC13C, LOC101866167, ST7L, LOC101866169, LOC101866170, LOC101866173, SS18, RAD23B, LOC101866176, VARS, LOC101866178, IFNGR1, SGK1, EPRS, TOE1, LOC101866189, LOC101866190, LOC101866191, ATP2B1, NFX1, ANAPC4, LOC101866197, LOC101866198, AQP4, LOC101866202, LOC101866203, LOC101866204, LOC101866205, RPS27L, URM1, LOC101866209, LOC101866210, EIF4B, LOC101866212, LOC101866213, LOC101866215, LOC101866216, KDELR2, NRBP1, LOC101866222, LOC101866223, NSUN5, YIPF5, LOC101866228, SYT11, LOC101866230, C7H14orf79, NT5C3A, CDC37L1, BLOC1S6, FARSA, LOC101866237, WDR45, CSDC2, ST8SIA3, LOC101866241, EIF2A, PIK3R1, CHD9, LOC101866248, USP39, HPCAL1, MICU1, FAM35A, LOC101866259, SLC5A11, LOC101866261, CAP1, CAMKK2, ADORA1, POGZ, LOC101866267, LOC101866269, TTC34, COPB2, LOC101866273, PLOD2, KERA, SCCPDH, RB1CC1, YPEL4, M6PR, LOC101866282, LOC101866284, FADD, GSS, LOC101866290, LOC101866291, CUX1, RTN3, MIEN1, RNFT1, CFL1, LOC101866301, FBLN7, LOC101866307, LOC101866308, CXXC5, UBQLN1, KMT2A, RAD50, LOC101866313, LOC101866314, LOC101866315, EBAG9, OXNAD1, LOC101866319, LOC101866320, ZNF8, LYPLAL1, DSCR3, CAMK2D, LOC101866327, GAS7, PAK3, LOC101866330, PGS1, NPDC1, CAPZA1, LOC101866336, VAPA, ETFB, KLC2, LOC101866341, LOC101866342, LOC101866343, TTI1, AARS, LOC101866346, TIAL1, RPS3A, SEPT4, TRAPPC2, LOC101866352, PAFAH1B1, LOC101866355, LOC101866356, ATP2C1, SERPINI1, LY6E, LOC101866362, NAPB, GUCY1A3, LOC101866367, LOC101866370, GATB, CALM3, PDPK1, LOC101866381, LOC101866385, LOC101866387, LOC101866388, LOC101866389, LOC101866390, DYNLL1, TMEM110, PCBP1, MRPL48, LOC101866396, LOC101866397, CDK14, MTMR2, OLFM3, SKA3, PAIP2, TMED9, BBX, RGS7, LARP7, LOC101866410, NARFL, LOC101866413, MAL2, CCNL2, VPS26A, LOC101866417, SDC4, LOC101866423, LOC101866428, LOC101866429, CYFIP2, LOC101866431, LOC101866433, RPL8, TUBB4B, LOC101866440, LOC101866442, SART3, LOC101866445, LOC101866446, ZNF266, LOC101866449, COQ2, LOC101866451, LOC101866452, LOC101866454, LOC101866456, LOC101866460, LOC101866466, MRFAP1, UBE2V2, NDUFAF7, LOC101866475, LOC101866477, SPIN1, FRZB, C11H12orf45, LOC101866481, LONP1, LOC101866483, LOC101866485, LOC101866486, LOC101866487, PNPLA6, LOC101866489, LDLRAD3, LOC101866492, DPP8, LOC101866495, SLFN11, LOC101866498, TOP1, FNTA, SUPT20H, LOC101866502, LOC101866503, DNAJC10, ADPGK, BZW1, RGS12, OS9, LOC101866510, CNOT7, IMPDH1, VAMP3, LOC101866514, LOC101866515, LOC101866516, ANXA11, VWA9, LOC101866521, LOC101866522, CRTAC1, STMN1, LOC101866526, MZT1, LOC101866530, HCFC1, SLAIN1, POLR2A, LOC101866539, LOC101866541, YWHAQ, KRI1, LOC101866544, LOC101866545, LOC101866547, ARHGEF9, CIZ1, LOC101866553, MRPL49, LOC101866555, ZSCAN18, LOC101866558, LOC101866560, FAM212A, LOC101866564, ELOVL1, PIAS3, SEC14L1, NDE1, OSGEP, LOC101866574, TSPYL2, LOC101866576, DENND6A, DLST, RGS17, TFPT, OGT, GUCY1B3, SNRNP70, LOC101866592, RAC1, FAM213A, GABRB1, LOC101866598, PXYLP1, POLR2G, LOC101866601, NCAM2, TUBB2B, LOC101866605, EIF2B5, PGAM1, TEX264, LOC101866613, LOC101866615, SLC27A4, CTCF, ARMT1, MBIP, LOC101866626, RPS17, FTSJ3, EPHA4, LOC101866632, FUCA1, LOC101866634, LOC101866635, LEMD3, LOC101866638, FAM107B, VMP1, GARNL3, CAPZB, LOC101866644, LOC101866645, LOC101866646, SUGP2, ITPRIP, LOC101866650, LOC101866651, LOC101866653, OCIAD1, GNB5, TBC1D2, XRCC6, MRPS35, HBS1L, POLR2L, LOC101866668, NDUFAB1, NUDT21, LOC101866672, PSMD6, C2H3orf18, NCOA6, KIAA0430, PAQR6, CAMLG, EIF2B2, LOC101866689, LOC101866691, ADAL, MAPRE2, TCERG1, CORO1A, PPP1R9A, GPALPP1, SMIM15, LOC101866700, VEZT, FAM161B, ATP6V1C1, LOC101866707, LOC101866708, LOC101866709, LOC101866711, LOC101866712, KCNAB1, TRAK2, POLD3, USP48, CDK2AP1, ACTR1A, RPS20, CETN2, AHCYL2, LOC101866730, NOLC1, LOC101866733, NAB2, LOC101866738, SORBS3, LMO7, LOC101866745, COCH, CD9, MRPL47, CDC42SE1, LOC101866752, NASP, RPS19, FHL3, LOC101866759, SMARCB1, LOC101866761, FMO5, SLC16A1, RPLP2, ZNF569, DRP2, KCNN3, LOC101866772, KTI12, LAPTM4B, CARS, LOC101866780, ARFIP2, CDO1, TANGO2, LOC101866786, CNBP, CRHBP, DDIT4, TRPC4AP, NDUFS8, CNP, SARS, LOC101866795, ZC3H10, C2CD2L, WASL, LOC101866801, FUBP1, SMARCD1, RSU1, PDCD10, ERLIN2, LOC101866807, LOC101866810, ARPC1A, FARSB, LOC101866813, LOC101866816, LOC101866817, PRMT5, LOC101866819, HNRNPR, LOC101866822, LOC101866823, LOC101866826, LOC101866827, TRPM8, HBP1, MYD88, LOC101866833, DST, LOC101866838, DUT, LOC101866840, TPT1, FKBP3, RAB9A, TIMM21, LOC101866846, SLC1A2, PDHX, GCLM, LOC101866851, SESTD1, LOC101866853, CLTC, LOC101866856, ARHGDIA, MRPL13, LOC101866859, PRKRIP1, TRNAU1AP, TDG, TBCCD1, HSP90AA1, ARG2, GPATCH4, ZNF330, LOC101866872, LOC101866873, REPS2, LOC101866877, TRIP11, LOC101866880, TPM4, ZCCHC14, PPP1R15B, RFFL, PLD3, GDAP1L1, TPD52L1, CLK4, RIC8B, VAT1, ZNF19, TIMMDC1, UHRF1BP1L, TMEM189, LOC101866903, NSF, ATP7B, VTI1B, GPHN, QSER1, LOC101866912, RECQL, LOC101866916, PGD, SPARCL1, TENM4, LOC101866921, PSAP, CTIF, TUBE1, ZNF207, LOC101866931, GMDS, LOC101866942, TARS, LOC101866945, LOC101866946, C16H17orf75, CFL2, ATP2B2, LOC101866952, LOC101866953, ELMOD3, LOC101866955, LOC101866956, XPC, SNTB2, PLAGL2, LOC101866961, MASP1, ZNF461, LOC101866965, ABI2, WDR70, RPS15A, CAST, GLCCI1, LOC101866972, LOC101866973, KIF16B, CCDC66, LOC101866976, LOC101866977, MYOC, LOC101866980, LOC101866981, LRIF1, EVL, LOC101866984, SLC3A2, HS6ST2, GORAB, TOP2B, LOC101866994, THRB, DCUN1D1, SLC16A14, LOC101866998, LOC101866999, CTPS1, RPP14, ERGIC2, FAM214A, LOC101867005, NAA60, USF2, TMEM106B, LOC101867011, POLR1A, USP21, PLOD3, MPDZ, LOC101867017, PSRC1, UBN1, CDS1, LDLRAD4, KCNA2, GOT2, CALB2, OTUD3, RPL3, LOC101867029, PLAA, TACC1, CAMSAP2, NUDT4, PTEN, LOC101867039, CXADR, LOC101867043, FYB, NR1H2, BCAT2, SUCLG1, ISCA1, MAB21L2, COQ4, CD24, LOC101867062, VCAN, SMAD1, LOC101867068, TFG, LOC101867070, CD59, LOC101867072, C1H1orf123, LOC101867074, LOC101867075, CASP6, EIF4E, MRPS22, TTPAL, ASH1L, B3GAT3, METAP1D, PDE1C, LOC101867091, LOC101867095, MED29, GJA1, LOC101867100, LOC101867102, LOC101867104, TUBA8, LOC101867106, LOC101867108, POU6F1, SUPT5H, LOC101867111, SC5D, GRAMD3, LOC101867114, PANK2, LOC101867116, LOC101867117, SPATA13, LOC101867119, C7H15orf57, FAM49B, LRPPRC, LOC101867123, KAT7, LOC101867125, RBM8A, NADK, LOC101867129, MYO1C, COPZ2, TIAM2, LOC101867134, PACSIN1, PPOX, FAM69A, LOC101867138, ZEB1, LOC101867142, LOC101867144, LOC101867146, LOC101867147, CNNM1, LOC101867150, LOC101867152, RBBP4, MRPL32, LOC101867155, PDGFRB, ZBTB8B, ARIH2, SH3RF1, SAFB2, B2M, ADGRF5, LOC101867175, LOC101867176, GCAT, C6H5orf42, PPID, SRSF10, RPL10, FKBP1A, CFLAR, TDP2, PA2G4, LOC101867186, AK1, TFCP2, LOC101867192, LOC101867194, LOC101867198, DLG2, LOC101867200, LOC101867201, LOC101867202, NUMB, LOC101867206, RBFOX3, LOC101867211, CHD4, LOC101867214, LOC101867216, LOC101867218, LOC101867221, PNKD, LOC101867224, LOC101867225, LOC101867228, LOC101867230, CCDC142, FAM206A, KCNK9, LOC101867236, GLT1D1, TTYH2, FXR2, PTP4A2, LOC101867242, DPP7, SMOX, LOC101867247, LOC101867248, LOC101867250, USP14, LOC101867256, GNA12, CCT4, NUDT6, LOC101867262, INPP5K, LOC101867264, VPS45, UBE2D3, BECN1, HSD17B12, WNT9A, TPP1, PPP2R1A, RPS6, PNRC1, PLP1, PSMC2, LOC101867281, TMEM117, DNAJC17, CLVS1, SCYL2, COMTD1, CACYBP, PDK2, MESDC2, SPPL3, GNB2, LOC101867298, LOC101867300, PKNOX1, ACADM, RHOG, MAPK12, LOC101867306, LOC101867308, CDC16, HID1, STX7, ABCF3, TAF13, LOC101867318, LOC101867320, LOC101867321, LOC101867322, TCAIM, RELA, TCEAL8, AIF1L, LOC101867329, LDHA, TMEM106C, LOC101867334, LOC101867336, LOC101867337, LOC101867338, B3GALT4, LOC101867341, LOC101867343, TAF1A, GRN, LOC101867349, MAPK13, LOC101867353, LOC101867355, LOC101867356, ATP2A2, SWI5, TBC1D22A, THNSL2, METTL18, QDPR, LOC101867369, CREBRF, POLE3, OMG, LOC101867375, LOC101867376, TMEM128, ARPC5L, PDXDC1, LOC101867384, LOC101867385, PNO1, PIGS, LOC101867389, LOC101867390, LOC101867393, LOC101867394, LOC101867397, STAMBPL1, RASSF4, FGF13, TSPAN31, POLE4, MYCBP2, LOC101867409, ANAPC10, CALB1, KIAA0319, BFAR, PRPS1, LOC101867415, LOC101867416, EFHD1, ATP5SL, LOC101867422, PPP1R13B, G3BP2, CASD1, NAAA, TBRG4, LOC101867428, LOC101867429, MACF1, MANBAL, LOC101867433, C6H5orf22, FAM173B, SLC17A7, LOC101867439, LOC101867440, SLC37A4, LOC101867442, HERC1, LOC101867445, MTG2, LOC101867448, LOC101867451, ZEB2, LOC101867455, NFKBIA, LOC101867461, LOC101867462, NEDD4L, LUC7L3, LOC101867465, DYNC2H1, MGME1, MPI, LGMN, PRDX1, ZDHHC9, LGALS8, MYO10, LOC101867482, ESYT1, PTBP3, LOC101867485, TBC1D7, C15H9orf40, LOC101867489, COPS2, DPP6, JOSD1, LOC101867498, LOC101867499, TUBA1B, LOC101867501, LOC101867502, LOC101867503, CD44, LOC101867505, PKIG, LAPTM4A, FTSJ1, ORMDL1, TAF1C, DZIP3, LOC101867518, TLK1, LOC101925033, LOC101925034, LOC101925035, LOC101925036, LOC101925037, RPL27A, PSMC1, PPIA, LOC101925042, LOC101925043, LOC101925044, LOC101925046, LOC101925047, NKAIN3, JAM3, USP9X, LOC101925053, NIT2, MAP2K6, CPNE6, BEND5, PCBP3, LOC101925064, PPP1R7, GLRX, KIAA1161, LOC101925072, LOC101925073, MRC2, CANX, LOC101925078, LOC101925082, RASAL2, LOC101925085, CCBL2, CLIP1, ZFYVE1, LOC101925091, DNAJC30, LOC101925093, ATF7, UBE3B, ZNF540, ALKBH3, LOC101925098, TRIM56, MAOB, UBE2Q1, EEF2, LOC101925105, LOC101925107, RAP1GAP, LOC101925109, STAT4, CCDC88A, LRBA, LOC101925114, LOC101925115, TSSC1, DDX52, NSUN6, LOC101925121, ARPC3, ITGB2, MBP, WARS, LOC101925127, OAZ1, CLIP3, CHRNB2, TRIT1, STAT1, LOC101925135, PITHD1, CACNA1G, CLDND1, LOC101925143, LOC101925145, TRIM8, NXT2, MYCBP, LOC101925152, LOC101925153, METAP2, WDR47, LOC101925156, LOC101925157, LOC101925159, LOC101925160, LOC101925165, LOC101925166, TBCB, LOC101925168, LOC101925173, TRAF2, EIF2S2, LOC101925179, USP45, NIPAL3, LOC101925186, MARK3, TAF9B, OAF, LAMTOR1, S100B, LOC101925201, SCAPER, CPEB1, DNM1L, LOC101925208, EDNRB, AGPAT4, ATG4C, MAP1B, LOC101925215, LOC101925218, PLCB4, SMYD5, PEA15, MCL1, LOC101925225, MAP1LC3B, ECHS1, LOC101925230, LOC101925231, ING4, ATP6V1D, CCDC59, PM20D1, TMEM222, LOC101925240, LOC101925243, FAM19A2, LOC101925245, LOC101925246, ARAF, CX3CR1, CAPNS1, TPM3, SPON1, DNAJB2, LOC101925256, LOC101925260, KLHL20, LOC101925263, TRIM13, LOC101925267, LOC101925268, LOC101925269, AKAP13, EEF1A1, LOC101925274, PRR13, LOC101925276, ACBD7, LOC101925283, LOC101925284, ERP29, LOC101925286, PEX19, LOC101925288, SCAMP3, STRADB, RAB11A, HEXA, LOC101925293, CA3, LOC101925298, COPS3, NKIRAS2, UBR5, CSNK1G1, LOC101925309, LOC101925310, LOC101925313, SLC17A5, SPTSSA, LOC101925321, LOC101925326, RECQL5, CCDC109B, ASNSD1, MAGOHB, LOC101925336, CRH, PRKAB2, LOC101925339, TBC1D1, GNG2, LOC101925343, KIDINS220, PLA2G15, LOC101925351, LOC101925352, RCAN1, FIP1L1, LOC101925357, LOC101925358, LOC101925359, PARP4, SARAF, TMPRSS5, LOC101925369, LOC101925372, LOC101925373, LOC101925376, ECE2, KPNA3, ZNF114, YARS2, LOC101925384, BORCS6, EIF2S1, LARGE, LOC101925388, AP4B1, LOC101925393, RAB13, TMEM198, LOC101925396, GOLGA2, LOC101925398, SMARCA2, LOC101925400, LOC101925403, LOC101925404, MED14, LOC101925408, GALC, LOC101925412, SLC6A15, FBXO3, LOC101925416, SLC16A6, SNX5, LOC101925423, ARPP19, ORC2, LOC101925431, TNPO3, C10H20orf27, RND1, LOC101925437, ATXN10, AQP1, LOC101925442, LOC101925444, SYNRG, TRAPPC8, LOC101925450, LOC101925451, RNF31, RYK, LOC101925458, DIDO1, AAMDC, SLC7A5, LOC101925462, LOC101925464, LOC101925466, APOD, GRSF1, YPEL5, LOC101925473, PLPPR1, HNRNPC, LOC101925476, LOC101925478, CCDC47, NAP1L1, LOC101925482, LOC101925484, SNAP47, ZC3H15, PITPNM3, LOC101925488, ACOT2, MTMR1, LOC101925491, ANGPT2, BCDIN3D, RPL28, INTS3, MRGPRF, ASPH, SLC20A2, LOC101925504, COPE, LOC101925507, LOC101925508, THUMPD2, AGAP3, LOC101925516, LOC101925517, LOC101925518, LOC101925519, LOC101925520, LOC101925521, RASSF2, WAC, NCOA1, LOC101925527, MFSD2A, LOC101925530, NEUROD1, ALS2, PSMD12, LOC101925536, LOC101925537, NOL3, SEPHS2, FAM122B, LOC101925543, EIF4A2, LOC101925546, SUDS3, NCOR1, PTK2, DGKB, LOC101925553, LOC101925554, APOA1BP, LOC101925556, MAPRE3, FUS, ELMO1, RNASE1, RPS6KB1, LOC101925565, LOC101925566, NACC2, SCN1A, KCNIP4, ZNF227, LOC101925575, PARP1, SNRPD3, CDC42EP4, LOC101925582, URI1, GOLGA7, POMP, GABARAPL2, USP46, BAG2, RBM5, GNPAT, FANCL, SKAP2, LOC101925596, LOC101925597, HTR2A, DYNLT3, KCTD4, PLEKHB1, LOC101925606, NOL4, STARD3NL, LDHB, POLR3H, LMO3, KIAA0368, MRPL18, LOC101925617, LOC101925619, PMP2, COG4, DNTTIP2, APOBEC3C, LOC101925625, BBS4, MRPL3, NR1D1, LOC101925630, PRRG1, LRRC49, CDC42EP3, NIFK, TOR1AIP1, LOC101925638, ALDOA, LOC101925640, LOC101925641, LOC101925642, MTF2, RTCA, LOC101925646, HNRNPA2B1, LOC101925648, LOC101925652, LOC101925653, ZNF484, SENP6, MAP3K5, KLHL2, PLCXD3, DIAPH2, FUT11, LOC101925667, LOC101925668, RNF43, LOC101925671, EXOC5, LOC101925674, LOC101925675, USP3, OMA1, PIGV, IL17RA, LOC101925680, SNAPC5, LOC101925682, ZNF564, LOC101925684, BBS2, NDUFB6, LOC101925691, DGKA, C14H11orf98, F11R, SLC41A1, LOC101925697, SOX17, C16H17orf62, SLC20A1, LOC101925701, FAM131A, LOC101925706, LOC101925708, SMARCA5, NPAS2, TADA3, LOC101925714, ADAM10, SYT16, RFX2, QTRTD1, TTLL11, TAOK1, CSE1L, PPP2R5C, LOC101925724, LOC101925725, B4GAT1, CINP, PIP4K2A, LOC101925729, TOMM40L, CDK4, LOC101925734, SLC25A30, CLN3, ADCY3, TNIK, LOC101925745, LOC101925749, LAPTM5, NECAP1, LOC101925755, LOC101925756, PRIMPOL, LOC101925760, LOC101925762, HLF, LOC101925764, LOC101925766, ADCK2, LOC101925770, LOC101925771, LOC101925774, TCEAL4, FOXO3, EML2, LOC101925783, LOC101925785, FOXRED1, LOC101925788, MSANTD1, IDH1, SNX12, MTHFD1L, LOC101925794, PPP1R1A, GABBR1, DNAJA1, LOC101925804, LOC101925806, LOC101925808, GLRX3, RPS19BP1, LOC101925812, LOC101925813, SNX2, ADNP2, TUBB, LOC101925817, LOC101925818, PSAT1, SCG3, LOC101925821, SLCO1A2, LOC101925823, LOC101925825, PRPF8, LOC101925828, LOC101925829, GLIPR1, C1H8orf59, NDUFS2, PAX6, NFIC, SLC25A48, LOC101925841, P4HA1, METTL9, LOC101925845, LOC101925846, PMM1, LOC101925848, CHD1L, TMEM206, FASTKD2, LOC101925854, LOC101925857, ACADVL, KPNA1, AQR, LOC101925865, GNG3, ANO2, ARRB1, SGK3, LOC101925873, WWOX, PTPRE, LOC101925876, LOC101925877, LOC101925880, PUM1, LOC101925886, LOC101925887, ZC3HC1, LOC101925890, LOC101925891, TBL2, LOC101925894, LOC101925895, LMBR1, LOC101925898, AREL1, ACO2, PTRF, PRKCZ, CALU, LOC101925910, FTL, LOC101925913, LOC101925914, CDKAL1, LOC101925916, LOC101925919, LOC101925920, IMPA1, PPFIA2, PPP1R11, RGS5, ULK2, SLC2A3, NDUFA11, DYNC1H1, BTBD1, LOC101925933, CDC42, IFI6, LOC101925938, FMO2, LOC101925944, LOC101925946, KLF6, TATDN1, SPECC1L, LOC101925950, ARHGEF17, LOC101925955, LOC101925956, LOC101925957, PFN2, INTS7, LOC101925960, SLC13A4, DOLK, MCAM, ARMCX1, PDSS1, AMN1, LOC101925971, NOV, DAGLB, LOC101925975, RARS, LOC101925977, OTUD5, LOC101925982, LOC101925983, LOC101925986, LOC101925987, CCDC3, AMBRA1, GABPB1, HNRNPA1, LOC101925997, LOC101925998, LOC101925999, SSR1, PCNP, CHEK1, LOC101926005, GNL1, MTCH1, MAP4, LOC101926009, PAXIP1, LOC101926011, BAZ2B, SV2A, LOC101926016, SERBP1, LOC101926019, ZC3H11A, HIBADH, SLC1A4, IPO13, DAZAP2, LOC101926027, LOC101926030, LOC101926032, IGFL4, LOC101926034, MAL, TXNDC11, LOC101926037, PRPF40B, RELL1, HMGCS1, SIAE, GPR22, SLC31A1, CLSTN2, LOC101926049, LOC101926050, LOC101926051, LOC101926052, LOC101926053, LOC101926055, HMBOX1, LOC101926058, SEL1L, KDM4A, LOC101926065, LOC101926066, LMAN2L, LOC101926068, FTSJ2, SLC25A3, ABCC5, CLGN, PSMB4, KCTD9, LOC101926078, LOC101926079, GLS, LOC101926083, LOC101926084, SNU13, MOBP, C11H12orf10, LOC101926091, LOC101926092, LOC101926093, KMT2E, LOC101926095, LOC101926096, ZNF134, LOC101926098, NSG1, GUCD1, NFIX, DDX6, GHITM, LOC101926107, TOPORS, LOC101926110, LOC101926113, CISD2, STRAP, NRN1, ISG20L2, LOC101926120, EMB, PHACTR3, LOC101926125, LOC101926127, DHDDS, FTH1, RBM26, LOC101926132, LOC101926133, LOC101926134, MRPS6, IL6ST, LOC101926142, LOC101926143, LOC101926145, ARHGAP33, RPL31, WDR41, PHB, ATP5S, KIAA1147, LOC101926155, LOC101926156, LOC101926158, POLR1E, LIPA, CEPT1, LOC101926166, ANXA5, HMGCL, LOC101926170, TTC32, COG1, SNX10, LOC101926178, GTF3C2, S100A1, SRSF3, HSPD1, ATG7, LOC101926189, MAP3K11, LOC101926195, TST, SEPT8, LOC101926199, LOC101926200, ISCU, LIMS2, EIF3L, BOD1, ZFAND6, LOC101926214, ATG16L2, CCK, NPTN, LOC101926220, AGT, PXK, FUNDC2, UBR2, VPS18, LOC101926227, ARF1, ZNF485, EXT1, RAB18, LOC101926235, PPA1, LOC101926238, RPL36, USP7, PTPRA, LOC101926244, LOC101926245, LOC101926247, HELQ, HMGCR, LOC101926250, LOC101926251, TMCC3, RPLP0, TRIP12, STRN4, FAM172A, CCNL1, LOC101926264, PDE8A, TSN, NTM, SQRDL, LOC101926272, ACSS3, C1H1orf27, LOC101926275, AKR1B1, LOC101926279, UTP6, BIN1, ADAR, TPD52, FLOT1, LOC101926289, LOC101926290, LOC101926291, LOC101926292, LOC101926293, LOC101926295, EYA1, LOC101926301, CERS4, POMGNT1, VMA21, LOC101926305, LOC101926306, ORC5, GOLT1B, ARHGAP26, LOC101926314, LOC101926315, PUS7L, SIRPA, CFAP44, NACA, TMEM129, AK2, BTD, RNF121, ZNF576, CMTM5, PCLO, LOC101926336, LOC101926337, CTGF, TM9SF3, ADD1, PHTF1, LOC101926342, RINT1, LOC101926345, LOC101926346, LOC101926347, LOC101926348, EIF4A1, ENG, LOC101926351, LOC101926352, LOC101926353, LOC101926354, STXBP5L, LOC101926357, CDC5L, FAM149B1, LOC101926361, LOC101926362, LOC101926364, RAB11B, TCEB1, VKORC1, LOC101926370, LOC101926371, LOC101926372, LOC101926373, LOC101926374, UBE2L3, PSMB6, GFOD2, SIDT1, HSP90AB1, SMARCD3, LOC101926382, ZNF420, LOC101926384, LOC101926385, ATG12, LOC101926392, SLC7A8, GTF2H2, LOC101926396, LOC101926397, LOC101926399, LOC101926400, KLHL12, LOC101926405, LOC101926407, NELFA, LOC101926409, POFUT1, ERCC2, LOC101926412, SYNJ2, TAF3, PREPL, LOC101926420, MPPED1, ATP6V1H, ASCC1, WLS, LOC101926429, LOC101926430, LOC101926431, LOC101926432, APP, CCT3, LOC101926435, LOC101926438, LOC101926439, RAMP3, YWHAB, MICALL1, SNX6, RPS3, APBB3, LOC101926450, NAF1, LOC101926452, ARMC8, KCTD2, B4GALNT1, OLA1, PRKACB, MYO5A, DBNL, LOC101926465, PPP1R17, LOC101926467, NAALAD2, ATXN2, KTN1, ELOVL6, LOC101926476, SART1, LOC101926481, LOC101926482, PPM1J, CREM, HSP90B1, HNRNPU, COQ9, SMAD9, LOC101926496, LOC101926498, TEX2, DLG5, DOT1L, BTBD11, IVNS1ABP, LOC101926507, BOLA3, TCAP, LOC101926511, PPP2R5A, TGDS, LOC101926514, LOC101926516, LOC101926518, SLC19A3, LOC101926524, PPP2R2C, LOC101926526, LOC101926527, GTF2E2, TSPAN13, LOC101926530, DCUN1D4, YWHAH, LOC101926536, LOC101926537, LOC101926538, LOC101926539, TMCO1, LOC101926541, ZNF526, HSD17B6, GTF2H4, LOC101926550, ALPL, EEA1, C19H19orf66, PRDM2, PTTG1IP, PABPC5, AP2B1, ATG10, HMOX1, C18H18orf32, HNRNPDL, STX17, DBP, RSL1D1, FAM63B, FEM1A, MBOAT2, WFS1, CD36, LOC101926578, SMDT1, PCMT1, LOC101926582, LOC101926583, LOC101926584, ANKS1B, LOC101926593, SCFD1, OLIG2, MTUS2, NUDT16L1, PRMT1, TRMT1, DGKG, DDX5, VPS33A, TRIM24, AMD1, CA11, LOC101926609, UMPS, CAMK2B, DNAJB9, LOC101926616, LMO2, XRN1, TATDN2, CS, TRIM67, FN3KRP, LOC101926628, LOC101926629, ATP6V1G2, ATR, LOC101926638, SRSF5, PSMB7, EIF3H, SLC39A6, ANP32E, LOC101926647, EIF2B3, PKP4, LOC101926653, LOC101926655, PARL, PAM, CADPS, NRCAM, DERL1, PPP5C, TSPAN15, FAM134C, LOC101926672, LOC101926675, TARDBP, SMPDL3A, SPOCK3, LOC101926685, SYN2, FADS2, LOC101926691, LOC101926692, GTF3A, NISCH, LOC101926696, HBB, BST1, POLR2B, RPL4, RPS4X, TECR, LOC101926703, GLUL, LOC101926705, LOC101926709, DCP1A, SLC30A9, TWSG1, GSK3A, BRD8, MAP1LC3A, NT5C2, PAK7, PAF1, LOC101926727, ZNF566, LOC101926729, LOC101926730, GORASP2, AP3D1, PCCA, SDR16C5, LDB2, LOC101926740, RNF34, TRH, ECE1, LOC101926748, RMDN2, LOC101926751, LOC101926753, PPP6C, CCDC106, CERS6, LRPAP1, LOC101926760, LOC101926762, LOC101926763, LOC101926765, LOC101926766, SRP54, TMEM100, LOC101926769, MAPK14, LOC101926771, RAB2A, LOC101926773, CSNK1D, UBB, PLEKHA3, LOC101926777, LOC101926779, RBM18, IGFBP5, NAGK, USO1, VPS51, STK40, ARPC1B, KIAA0930, LOC101926795, FAM107A, LOC101926798, RHOT1, LOC101926803, LOC101926806, LOC101926807, DDX19A, GPR37L1, VPS35, PFKFB3, RPL19, LOC101926815, LOC101926818, ASPN, RASA2, APEX1, ABCE1, FSD1L, SRSF6, AP4S1, LOC101926828, FAM73A, AATF, GARS, LAP3, NKAP, SLC25A14, ELL2, LOC101926840, RHOJ, AHCYL1, LOC101926845, HMGN5, OLFML3, LOC101926849, GFAP, KRT222, RPS10, LOC101926855, LOC101926856, PKIB, LOC101926858, ANP32A, DBT, LOC101926865, TUSC2, LOC101926867, SRSF2, TM6SF1, DCTN2, LOC101926871, PWP1, LOC101926873, SUB1, LOC101926875, LOC101926876, LOC101926877, LOC101926878, LOC101926879, LOC101926882, DHX9, MAPK4, KIAA1671, CLIP2, EXOC4, TUBB2A, TOP1MT, GGA3, LOC102114950, GOLIM4, GRIN1, EIF3D, EGR2, PDP2, ENPP4, ATP5F1, DRG2, NPTX1, ATG4B, TBC1D9, SRSF11, KCNAB2, BTG1, ACACB, FAM103A1, LOC102116067, OTUD6B, BCAP29, UPRT, TUFM, ITGAV, RASGRF1, WSB1, DNASE2B, SLC44A1, LRP12, NDUFB9, DDX21, LOC102116582, MACROD2, CDK5RAP3, HSPA13, CREBL2, EIF5, CEP19, FAXC, HTATIP2, HNRNPAB, BACE1, UPF2, UBA3, DLGAP1, PRKCB, CERS5, TOLLIP, ERGIC1, ESRRG, MAGIX, ACTR2, GAP43, SCAF4, PUDP, FAM171B, GOLGA5, SERPINF1, ZNF596, LOC102117433, MTHFR, SYNE1, GABBR2, TDRKH, SUSD5, CEP68, TFB2M, NMNAT2, USP54, APOL2, WDR4, DNASE2, ARL4A, NKAIN2, SLC38A2, ARL1, PAQR8, ZZZ3, NBR1, RBBP6, ACYP2, GPS1, TSC22D1, SLC30A5, CSNK1A1, SET, GRB2, RPS6KA2, FH, SMG7, ASAH1, STAT3, RNPS1, ZBTB33, CNST, FOXJ2, SAMD13, SEC62, RPF2, C6H5orf51, FAM76B, RNASE4, COPS5, ANKH, GCDH, GPCPD1, CHN1, CDK20, GDI2, LHFP, TWISTNB, DIP2B, FMNL2, PSME4, RAB12, CCND2, DDX47, KIF21A, TNRC6A, PDS5A, CHRM1, LOC102119662, LAMP2, RFK, PON2, C1H1orf43, LOC102119972, LOC102119981, GNB1, LRCH3, FNBP1, MIEF2, DUSP26, C4H6orf62, AKIP1, TARSL2, AK3, LOC102120338, RAD52, LMO4, SERPIND1, COPS7A, NUAK1, CUL4B, LOC102120633, CELF3, NBEA, CEP76, PNRC2, MRPL39, SPAG9, SNAP91, SLC39A14, SLC45A4, FGD4, CBX1, LPIN2, TASP1, ATP5G3, ETV3, NQO1, SSR3, TRA2A, SLC36A4, MPZL1, MAGI3, RNF138, GZF1, HEY2, PRICKLE4, SORL1, BABAM1, WDR12, CNOT6, LIG4, CAV2, ZNF606, ESAM, BNIP3L, PEX12, HECTD2, KLHL32, CNOT6L, LRSAM1, GPRC5C, SNAP29, OGDH, FAM131B, RPE65, GTF2I, NARS2, COL4A1, ARHGEF3, ATXN1, ROBO3, FBXL5, CASC4, ARHGAP5, GOLPH3L, SLA, BCAS3, ABHD13, LOC102122910, PLEKHA1, LOC102122986, SAP130, RANBP2, EXOSC9, TP53BP2, GRIN2A, EPB41L2, ARHGAP21, PLIN3, TERF2IP, NRDC, AES, KCNJ3, TGOLN2, LOC102123567, ROBO4, UNC13A, PJA1, LOC102123651, HSD17B4, LOC102123677, SPRED1, DDOST, PPP1R3C, ATP5A1, SLC2A13, TSR1, CEBPZ, TROVE2, ELOVL2, MYBPHL, RNF8, TSC1, RBM17, ZCCHC24, MAP6D1, RALA, LCMT1, NDUFV1, HAPLN1, LOC102124348, TMEM230, EPHB6, CWC22, RETSAT, FAM53C, KCTD12, MRPL42, RHOU, DPYSL2, PSMD10, PLS3, PPM1A, HEPACAM, MAP2K4, ORC4, MSANTD4, NUDCD3, HINT3, RMND5A, RHOB, PPP2R2B, SGSM2, CELSR2, GALNT1, ANKRD12, AIM1, ZFP36L1, NDRG1, RFTN1, LRFN3, NAPA, PGK1, PTPRD, LPCAT2, WSB2, PUM2, CTSD, LMNA, TGIF1, ZNF135, EEF1B2, LOC102125780, TENM3, SLC35A4, LOC102126003, APPL1, RNF41, ATG2B, PPT1, ZNF131, RGS4, RPL30, CIAPIN1, USP47, IPO7, DIXDC1, PYCRL, DDA1, HSPBP1, RNF40, NUS1, RAB8B, KDM5B, TIMM44, SFXN5, PRDM11, LOC102126833, CHMP1A, VPS11, GNG12, CDH7, SHROOM2, NRXN1, EDIL3, C19H19orf60, PRNP, S1PR1, EPB41L1, ADGRB3, ARRDC4, ASB2, PEBP1, ATPAF1, HSDL1, MAP6, ATP6V0E2, GNA13, ICA1, TSPAN7, UGT2B9, LOC102127938, SLC22A15, TAF15, PMPCB, TANK, GJB1, BASP1, IL17RC, SNX3, SLC25A12, PSMD11, SLC35F1, THOC2, PTPN5, CWF19L2, CRYAB, PHGDH, ARHGAP44, DGCR2, RPS11, KIF5C, CTXN3, SELENBP1, TNFAIP1, ANKRD28, LOC102128739, PPP1R14A, PHF24, PCDH9, PPP1R15A, DUS2, LIN7C, TPRG1L, TMEM221, MMGT1, TRAM1L1, NFU1, ECD, NAA50, DPYSL3, SHANK2, KCTD18, NSL1, CRY1, TTC1, SCN2B, CADM3, IDH3B, KIF1A, DCAF7, RELN, CCDC91, LPL, KPNA6, CCNY, DLX1, SLC25A6, EID1, DBR1, LRRC20, QRICH1, ORC3, MTERF2, PSMD14, SUMO1, VBP1, REXO2, EGFLAM, MYH10, ABI1, PLXNC1, ZMAT4, KBTBD11, KHK, NCOA2, HIGD1A, EXOC6B, IK, ZBED5, DDX24, BAALC, SAP30BP, MYLK, HAGH, LOC102130747, LGI2, DCAF5, FRMD4A, SECISBP2L, MPDU1, MANEA, TIMM10B, CIPC, CALM1, JRK, AP2M1, YWHAG, UBE3D, CRIM1, E2F6, BDP1, HSPA8, SIX4, C16H17orf107, LOC102131468, CCNJL, PCDH17, MCTP1, SACM1L, CACNA2D1, GNAO1, LOC102131764, MBNL1, LOC102131888, ZFYVE16, CEP112, TTC9B, C3H7orf49, QSOX1, UBXN2B, CA5B, LRP1B, ACSL4, LOC102132252, LOC102132314, PPP1R2, TMED2, MTCH2, NTRK2, RBX1, ADORA2A, PNPLA8, GRIK1, CHCHD10, CRYM, KCNIP1, PTPRN2, RAP1B, WDR33, UCHL1, CTNNA1, RMDN1, JADE3, MOAP1, SDCBP, LRRC14, PPP1CB, PAMR1, FAR2, CD83, FAM120A, GPR12, GPNMB, TUSC3, RGS9, LOC102133631, TCAF1, RAB21, SNRPN, ACADSB, ZNF638, SLC27A6, NR1D2, NDUFA7, COTL1, KLHDC4, ACADL, MFGE8, NOVA1, LOC102134176, C13H2orf49, ADGRB2, TGFBR2, DNAJC28, ADNP, DDX55, B4GALT7, MTMR4, MAPK11, EPHA7, PPP3CA, SNAP25, SLC39A10, C6H5orf30, NBPF1, IMMT, TUB, IKZF5, CDH2, USP10, CIT, IRAK1, WDR20, SAR1A, FBLN2, PTCD2, LOC102135041, MEF2C, IKBKAP, SPRYD3, TMEM205, CDC25B, TMTC1, UBE4A, STT3A, MAP7, STIP1, CLU, HIRIP3, AURKAIP1, HPS1, RPL18A, GIMAP4, MRE11A, EI24, MTUS1, FHOD1, RIC3, APTX, MOXD1, CDKN1A, MFSD14A, MAGI1, ASB8, SH3BP4, ERI3, CNIH1, LRRTM3, FAM168B, DPYSL5, LOC102136518, TMEM25, P4HB, IQSEC3, LOC102136630, SLC39A1, NAT6, PDYN, CNKSR2, MSH3, BCO2, TTC5, PRPF4, ZNF624, MYRIP, BTRC, SLC25A17, LUZP2, PBK, SNRK, LANCL2, ARL6IP1, LOC102137003, ZNF664, RNF141, NSMCE3, CPT2, LOC102137182, INPP5F, AGPAT3, C3H21orf91, GTF3C1, LOC102137297, NKIRAS1, MALRD1, RSRC1, LSS, KIZ, RBM22, EFNB3, LAMP5, DIABLO, LANCL1, ASPA, TMEM161A, SLC7A6OS, CMKLR1, HHAT, HNRNPA3, GRIK2, SDAD1, BBIP1, ZNF658, GATM, WBP2, SAMD9L, SLC35A2, MGST3, VAMP1, MTPN, TAB3, LOC102138501, DCTN1, SLC19A2, MAP1A, GTDC1, PPP1R21, MTAP, PSEN1, ASPHD2, SRI, CTTNBP2NL, UBE2Z, SLC25A26, FAM160B1, LOC102138874, DNAJC15, PDCD4, RNF216, BRINP2, PFN1, KCNMA1, CNPPD1, LOC102139305, IFT57, NPTXR, ZHX3, SLC4A1AP, LOC102139510, GABRA1, CDH24, LRRC8D, RNF220, RAB8A, NIF3L1, PKD2, WDR92, RIC8A, PACS1, ALDH9A1, NME6, ACTB, USP11, UBE2A, CDH9, YOD1, MARCKS, PPIG, PTGES2, LTN1, LOC102140087, VAPB, POC1B, RUFY3, TMEM123, MAP4K5, BCL2L1, POLR2H, TEX30, YWHAE, UBE4B, PIK3R4, PTGES3, MAP3K7, ABCG2, PLCB1, UBXN4, AGAP1, HPGD, ZFP90, C1D, POLR3G, WDR61, PSME1, TRIM37, ZSWIM3, TAC1, FIG4, IL17RB, WDR11, TNPO2, PSMD13, TERF1, NEBL, WDFY2, ATRNL1, GPN1, TSPAN14, CNTNAP2, NAV1, PPM1K, ZRANB2, LOC102141936, CDC42SE2, NIN, SRRM1, OSGIN2, GSPT1, LOC102142214, PCSK1, TICAM2, IRF9, KLHL23, PCDHB6, LOC102142503, LOC102142548, GPX4, SKP1, KAT2B, DDX17, LOC102142811, GDI1, KIAA2026, ANKRD46, SHISA9, TTC17, CRB1, IREB2, ZCCHC17, ATP6V0D1, HMGA1, PNMA3, CELF2, SLC6A1, WASF1, HADHB, LYST, TMUB2, IPMK, ZNF808, GRPEL1, GPM6A, GM2A, PRELP, PITPNA, BMS1, PHLDB1, PLPP7, INIP, NBN, NMT2, PHACTR1, MTMR10, ASAP1, PARG, IFIT1, MFSD5, HSPA4L, TAX1BP3, SLC35A5, LOC102144252, LOC102144280, TXNDC5, CDH6, DNAJB4, CLSTN1, RAD21, CGGBP1, COPZ1, ADGRL3, NAP1L5, SPOCK2, AP3M2, DHCR24, SH3BGRL3, NAMPT, IKZF4, SSPN, CDC40, NUDT17, LOC102145186, SLC25A18, UBE2B, FAM222B, BAIAP3, GRM1, MRPS10, SSB, FAM19A1, ETV1, AP2A1, SKIV2L2, TBC1D9B, C15H9orf91, RB1, NEFH, DLX6, C3H7orf60, RAB28, FKTN, ATXN7L3, SDC2, LAMA1, CIRBP, C13H2orf15, CAT, MLC1, PRDX2, PKN1, STX1A, GPRC5B, ELK1, SCAMP1, TRIM9, THAP10, TMEM229B, TCF4, COMMD10, DHX58, PIAS2, NUP153, EFR3A, INSIG1, ADCY1, LOC102147033, RANBP3, FCGR1A, LOC102147203, PTP4A1, LOC107126545, LOC107126752, LOC107127449, LOC107127883, ZSCAN31, LOC107129917, CEP68
原始数据
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文献解读
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