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The chicken GABAA receptor alpha 1 subunit: cDNA sequence and localization of the corresponding mRNA.

Brain Res. Mol. Brain Res.1991 Mar;9(4):333-9
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摘要

We report the sequence of a complementary DNA (cDNA) that encodes the chicken GABAA receptor alpha 1 subunit, which is extremely homologous to mammalian alpha 1 subunits. The distribution of alpha 1 subunit transcripts is shown to correlate mainly, but not completely, with the previously-reported pattern of benzodiazepine type I (BZI) binding sites in the avian brain. These results suggest that the alpha 1 subunit may not necessarily be restricted to receptors having BZI pharmacology.

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