例如:"lncRNA", "apoptosis", "WRKY"

SECRET AGENT and SPINDLY have overlapping roles in the development of Arabidopsis thaliana L. Heyn.

J. Exp. Bot.2006;57(4):865-75. Epub 2006 Feb 10
Lynn M Hartweck 1 , Ruth K Genger , William M Grey , Neil E Olszewski
Lynn M Hartweck 1 , Ruth K Genger , William M Grey , Neil E Olszewski

[No authors listed]

Author information
  • 1 Department of Plant Biology, University of Minnesota, 250 Biological Sciences Center, 1445 Gortner Ave., St Paul, 55108, USA.

摘要


O-GlcNAc transferase (OGT) catalyses transfer of GlcNAc (N-acetylglucosamine) to serine or threonine of proteins. The Arabidopsis OGTs, SECRET AGENT (SEC) and SPINDLY (SPY) have overlapping functions during gametogenesis and embryogenesis. SPY functions in a number of processes including circadian, light, and gibberellin (GA) responses. The role of SEC in plant development and GA signalling was investigated by determining the phenotypes of sec-1 and sec-2 plants and the expression pattern of SEC. Similar to SPY, SEC transcripts were ubiquitous. Although there is no evidence of transcript-level regulation by other factors, SEC mRNA levels are elevated in spy plants and SPY mRNA levels are elevated in sec plants. sec-1 and sec-2 plants exhibited few of the defects observed in spy plants and had wild-type GA responses. Compared with wild type, sec plants produced leaves at a reduced rate. Haplo-insufficiency at SEC in a spy ga1 double mutant background suppressed spy during germination and enhanced the production of ovaries with four carpels by spy. By contrast, SPY haplo-insufficiency in a sec ga1 double mutant background caused a novel phenotype, production of a proliferation of pin-like structures instead of a floral shoot. These results are consistent with SEC function overlapping with SPY for leaf production and reproductive development.

基因