MAPKAP kinases - MKs - two's company, three's a crowd.

Nat. Rev. Mol. Cell Biol.2006 Feb;7(2):120-30

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Downstream of mitogen-activated protein kinases (MAPKs), three structurally related MAPK-activated protein kinases or MKs) - MK2, MK3 and MK5 - signal to diverse cellular targets. Although there is no known common function for all three MKs, these kinases are involved in important processes: MKs regulate gene expression at the transcriptional and post-transcriptional level, control cytoskeletal architecture and cell-cycle progression, and are implicated in inflammation and cancer.

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MAPKAP kinases - MKs - two's company, three's a crowd.

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