Chromosomal fragmentation is the major consequence of the rdgB defect in Escherichia coli.

Genetics. 2006 Feb;172(2):1359-62. Epub 2005 Dec 01

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The rdgB mutants depend on recombinational repair of double-strand breaks. To assess other consequences of rdgB inactivation in Escherichia coli, we isolated RdgB-dependent mutants. All transposon inserts making cells dependent on RdgB inactivate genes of double-strand break repair, indicating that chromosomal fragmentation is the major consequence of RdgB inactivation.

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Chromosomal fragmentation is the major consequence of the rdgB defect in Escherichia coli.

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