Identification of an HptB-mediated multi-step phosphorelay in Pseudomonas aeruginosa PAO1.

Res. Microbiol.2006 Mar;157(2):169-75. Epub 2005 Sep 07

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We herein demonstrate that the hybrid sensor PA1611 carries out specific signal transduction, through HptB (PA3345), to the response regulator PA3346 in Pseudomonas aeruginosa PAO1. As assessed by phenotypic changes in the hptB deletion mutant, the pathway is likely to be involved in the regulation of flagellar activity, the chemotaxis response, twitching motility, and biofilm formation in the bacteria.

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Identification of an HptB-mediated multi-step phosphorelay in Pseudomonas aeruginosa PAO1.

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