Smg1 nonsense mutations do not abolish nonsense-mediated mRNA decay in Drosophila melanogaster.

Genetics. 2005 Sep;171(1):403-6. Epub 2005 Jun 18

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摘要

Smg1 is a key component of nonsense-mediated decay (NMD) in Caenorhabditis elegans and mammals. Here we report that two nonsense alleles of the ortholog of Smg1 do not affect NMD in Drosophila melanogaster.

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Smg1 nonsense mutations do not abolish nonsense-mediated mRNA decay in Drosophila melanogaster.

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