Alginate lyase (AlgL) activity is required for alginate biosynthesis in Pseudomonas aeruginosa.

J. Bacteriol.2005 Jun;187(11):3869-72

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To determine whether AlgL's lyase activity is required for alginate production in Pseudomonas aeruginosa, an algLdelta::Gm(r) mutant (FRD-MA7) was created. algL complementation of FRD-MA7 restored alginate production, but algL constructs containing mutations inactivating lyase activity did not, demonstrating that the enzymatic activity of AlgL is required for alginate production.

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Alginate lyase (AlgL) activity is required for alginate biosynthesis in Pseudomonas aeruginosa.

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