Stem cells and cancer; the polycomb connection.
Cell. 2004 Aug 20;118(4):409-18
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摘要
Proteins from the Polycomb group (PcG) are epigenetic chromatin modifiers involved in cancer development and also in the maintenance of embryonic and adult stem cells. The therapeutic potential of stem cells and the growing conviction that tumors contain stem cells highlights the importance of understanding the extrinsic and intrinsic circuitry controlling stem cell fate and their connections to cancer.
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基因功能
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原始数据
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文献解读
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