例如："lncRNA", "apoptosis", "WRKY"

Genome evolution in yeasts.

Nature. 2004 Jul 01;430(6995):35-44
Bernard Dujon 1 , David Sherman , Gilles Fischer , Pascal Durrens , Serge Casaregola , Ingrid Lafontaine , Jacky De Montigny , Christian Marck , Cécile Neuvéglise , Emmanuel Talla , Nicolas Goffard , Lionel Frangeul , Michel Aigle , Véronique Anthouard , Anna Babour , Valérie Barbe , Stéphanie Barnay , Sylvie Blanchin , Jean-Marie Beckerich , Emmanuelle Beyne , Claudine Bleykasten , Anita Boisramé , Jeanne Boyer , Laurence Cattolico , Fabrice Confanioleri , Antoine De Daruvar , Laurence Despons , Emmanuelle Fabre , Cécile Fairhead , Hélène Ferry-Dumazet , Alexis Groppi , Florence Hantraye , Christophe Hennequin , Nicolas Jauniaux , Philippe Joyet , Rym Kachouri , Alix Kerrest , Romain Koszul , Marc Lemaire , Isabelle Lesur , Laurence Ma , Héloïse Muller , Jean-Marc Nicaud , Macha Nikolski , Sophie Oztas , Odile Ozier-Kalogeropoulos , Stefan Pellenz , Serge Potier , Guy-Franck Richard , Marie-Laure Straub , Audrey Suleau , Dominique Swennen , Fredj Tekaia , Micheline Wésolowski-Louvel , Eric Westhof , Bénédicte Wirth , Maria Zeniou-Meyer , Ivan Zivanovic , Monique Bolotin-Fukuhara , Agnès Thierry , Christiane Bouchier , Bernard Caudron , Claude Scarpelli , Claude Gaillardin , Jean Weissenbach , Patrick Wincker , Jean-Luc Souciet
Bernard Dujon 1 , David Sherman , Gilles Fischer , Pascal Durrens , Serge Casaregola , Ingrid Lafontaine , Jacky De Montigny , Christian Marck , Cécile Neuvéglise , Emmanuel Talla , Nicolas Goffard , Lionel Frangeul , Michel Aigle , Véronique Anthouard , Anna Babour , Valérie Barbe , Stéphanie Barnay , Sylvie Blanchin , Jean-Marie Beckerich , Emmanuelle Beyne , Claudine Bleykasten , Anita Boisramé , Jeanne Boyer , Laurence Cattolico , Fabrice Confanioleri , Antoine De Daruvar , Laurence Despons , Emmanuelle Fabre , Cécile Fairhead , Hélène Ferry-Dumazet , Alexis Groppi , Florence Hantraye , Christophe Hennequin , Nicolas Jauniaux , Philippe Joyet , Rym Kachouri , Alix Kerrest , Romain Koszul , Marc Lemaire , Isabelle Lesur , Laurence Ma , Héloïse Muller , Jean-Marc Nicaud , Macha Nikolski , Sophie Oztas , Odile Ozier-Kalogeropoulos , Stefan Pellenz , Serge Potier , Guy-Franck Richard , Marie-Laure Straub , Audrey Suleau , Dominique Swennen , Fredj Tekaia , Micheline Wésolowski-Louvel , Eric Westhof , Bénédicte Wirth , Maria Zeniou-Meyer , Ivan Zivanovic , Monique Bolotin-Fukuhara , Agnès Thierry , Christiane Bouchier , Bernard Caudron , Claude Scarpelli , Claude Gaillardin , Jean Weissenbach , Patrick Wincker , Jean-Luc Souciet
+ et al

[No authors listed]

Author information
  • 1 Unité de Génétique Moléculaire des Levures, URA 2171 CNRS and UFR 927 Université Pierre et Marie Curie. bdujon@pasteur.fr

摘要

Identifying the mechanisms of eukaryotic genome evolution by comparative genomics is often complicated by the multiplicity of events that have taken place throughout the history of individual lineages, leaving only distorted and superimposed traces in the genome of each living organism. The hemiascomycete yeasts, with their compact genomes, similar lifestyle and distinct sexual and physiological properties, provide a unique opportunity to explore such mechanisms. We present here the complete, assembled genome sequences of four yeast species, selected to represent a broad evolutionary range within a single eukaryotic phylum, that after analysis proved to be molecularly as diverse as the entire phylum of chordates. A total of approximately 24,200 novel genes were identified, the translation products of which were classified together with Saccharomyces cerevisiae proteins into about 4,700 families, forming the basis for interspecific comparisons. Analysis of chromosome maps and genome redundancies reveal that the different yeast lineages have evolved through a marked interplay between several distinct molecular mechanisms, including tandem gene repeat formation, segmental duplication, a massive genome duplication and extensive gene loss.

© 2017 biocloud.net版权所有 ICP证：京10042835号