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Expression analysis of the Drosophila pipsqueak family members fernández/distal antenna and hernández/distal antenna related.

Dev. Dyn.2004 Jun;230(2):361-5. doi:10.1002/dvdy.20046
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摘要


The "pipsqueak" family is composed of proteins that contain a pipsqueak motif, a previously characterised DNA binding domain, and thus represents a new family of potential transcription factors. Previous functional characterisation of several Drosophila genes encoding pipsqueak domain-containing proteins has shown their crucial role in development. Here, I report the embryonic, larval, and pupal expression pattern of two Drosophila genes, fernández/distal antenna and hernández/distal antenna related, which encode protein members of the pipsqueak family with similar pipsqueak motifs. Furthermore, I show that, consistently with their expression pattern, these two genes are required in the nervous system during the embryonic development.

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