Molecular cloning and characterization of three adult rat beta-globin gene promoters.
Biochim. Biophys. Acta. 2004 May 25;1678(2-3):145-9
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摘要
We analyzed the promoter regions of the adult rat beta (IIbeta, IIIbeta, and 0beta)-globin genes. The results indicated that (1) the activities of the minimal promoters of these three genes are proportional to the gene expression levels in vivo, and (2) erythroid-specific repressor regions are located immediately upstream of the minimal promoter sequences and are regulated by the same transcription factor.
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基因功能
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原始数据
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文献解读
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