The ever-increasing complexities of the exon junction complex.

Curr. Opin. Cell Biol.2004 Jun;16(3):279-84

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摘要

Over the past decade many studies have revealed a complex web of interconnections between the numerous steps required for eukaryotic gene expression. One set of interconnections link nuclear pre-mRNA splicing and the subsequent metabolism of the spliced mRNAs. It is now apparent that the means of connection is a set of proteins, collectively called the exon junction complex, which are deposited as a consequence of splicing upstream of mRNA exon-exon junctions.

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The ever-increasing complexities of the exon junction complex.

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