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Unraveling the pathway of lipoic acid biosynthesis.

Chem. Biol.2004 Jan;11(1):10-2
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摘要


Lipoic acid is almost universally required for aerobic metabolism. However, the mechanism for its synthesis and incorporation into proteins has remained elusive. A groundbreaking study published in the December issue of Chemistry & Biology uncovers critical features of the lipoic acid biosynthetic pathway.

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