Molecular cloning of PP2Ceta, a novel member of the protein phosphatase 2C family.

Biochim. Biophys. Acta. 2003 Nov 30;1630(2-3):130-7

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摘要

We have cloned a novel member of the mouse protein phosphatase 2C family, PP2Ceta. Sequence analysis suggests that PP2Ceta, PP2Czeta and NERPP-2C constitute a unique subgroup of the PP2C family. PP2Ceta had extremely low activity against alpha-casein compared with PP2Calpha and was localized mainly in cell nuclei, suggesting that PP2Ceta dephosphorylates a unique nuclear protein(s) in the cells.

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Molecular cloning of PP2Ceta, a novel member of the protein phosphatase 2C family.

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