Elastase involvement in extracellular and intracellular collagen degradation during postpartum involution of the uterus.

Bull. Exp. Biol. Med.2003 Aug;136(2):206-8. doi:10.1023/a:1026395613444

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The location of elastase in rat uterus during its postpartum involution was studied by electron histochemical method. Intense extracellular activity of the enzyme was detected: the reaction product was found on the cytolemma of smooth-muscle cells and, to a lesser extent, on the cytolemma of macrophages and fibroblasts and on adjacent collagen fibrils. The reaction product was also found in vacuoles with collagen in macrophages and fibroblasts.

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Elastase involvement in extracellular and intracellular collagen degradation during postpartum involution of the uterus.

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