Human sperm associated antigen 4 (SPAG4) is a potential cancer marker.

Cell Tissue Res.2004 Feb;315(2):279-83. doi:10.1007/s00441-003-0821-2. Epub 2003 Nov 12

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Using a combination of database screening and polymerase chain reaction analyses we have determined the sequence and structure of the human sperm tail associated gene is a 12-exon gene spanning approximately 5.2 kb on chromosome 20q11.23. It is expressed in a limited number of normal tissues, notably the pancreas and testis, but is switched on and greatly upregulated in a wide range of neoplastic tissues. The data therefore strongly suggests that duanyu1842G4 expression is a potential clinically relevant cancer marker.

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Human sperm associated antigen 4 (SPAG4) is a potential cancer marker.

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