The dinB operon and spontaneous mutation in Escherichia coli.
J Bacteriol. 2003 Jul;185(13):3972-7. doi:10.1128/JB.185.13.3972-3977.2003
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摘要
Apparently conflicting data regarding the role of SOS-inducible, error-prone DNA polymerase IV (DinB) in spontaneous mutation are resolved by the finding that mutation is reduced by a polar allele with which dinB and neighboring yafN are deleted but not by two nonpolar dinB alleles. We demonstrate the existence of a dinB operon that contains four genes, dinB-yafN-yafO-yafP. The results imply a role for yafN, yafO, and/or yafP in spontaneous mutation.
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基因功能
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原始数据
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文献解读
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