The yggH gene of Escherichia coli encodes a tRNA (m7G46) methyltransferase.
J Bacteriol. 2003 May;185(10):3238-43. doi:10.1128/JB.185.10.3238-3243.2003
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摘要
We cloned, expressed, and purified the Escherichia coli YggH protein and show that it catalyzes the S-adenosyl-L-methionine-dependent formation of N(7)-methylguanosine at position 46 (m(7)G46) in tRNA. Additionally, we generated an E. coli strain with a disrupted yggH gene and show that the mutant strain lacks tRNA (m(7)G46) methyltransferase activity.
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基因功能
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原始数据
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文献解读
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