Identification and expression of Ima, a novel Ral-interacting Drosophila protein.

Gene Expr. Patterns. 2002 Dec;2(3-4):289-96

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摘要

We report the identification of Ima, a novel Drosophila MAGUK-like protein, which contains two WW and four PDZ protein interaction domains and interacts with the small GTPase dRal in the yeast two-hybrid system and pull-down assays. The gene is expressed in distinct spatiotemporal patterns throughout embryonic development. Overexpression of Ima interferes with normal Drosophila development, indicating that the gene functions in a tissue specific manner.

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Identification and expression of Ima, a novel Ral-interacting Drosophila protein.

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