Expression of gamma-adducin is associated with regions of morphogenetic cell movement in the chick embryo.

Gene Expr. Patterns. 2002 Dec;2(3-4):213-7

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The adducin family of cytoskeletal proteins are known to mediate actin driven cell movements. Here we describe the cloning and expression pattern of a gene encoding gamma-adducin in the chick embryo. Expression of this gene is strikingly restricted to the epithelial cell layer (with a few exceptions including emerging notochord and lateral mesoderm). Gamma-adducin is detected at particularly high levels in cell populations undergoing important morphogenetic movements, such as epiblast approaching the primitive streak, regressing spinal cord primordia and closing neural tube.

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Expression of gamma-adducin is associated with regions of morphogenetic cell movement in the chick embryo.

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