Cloning, chromosome localization and features of a novel human gene, MATH2.

J. Genet.2002 Apr;81(1):13-7. doi:10.1007/bf02715865

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We report cloning and some features of a novel human gene, MATH2, which encodes a protein of 337 amino acid residues with a basic helix loop helix domain and exhibits 98% similarity to mouse Math2. Results of Northern blot analysis revealed two transcripts of the MATH2 gene of 1.7 kb and 2.4 kb in human brain. We localized MATH2 to chromosome 7 at 7p14-15 by matching with the Human Genome Sequence Database. Human MATH2 and mouse Math2 may have the same functions in the nervous system.

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Cloning, chromosome localization and features of a novel human gene, MATH2.

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